Education

1992~1996 China Agricultural Univercity,physiology，B.S
2000~2001 Tokyo University of Agriculture and Technology,physiology of domestic animal,Short-term exchange students

1996~2001 China Agricultural Univercity,physiology，PhD

Professional Experience

2001~2002 University of Kansas，postdoctoral
2002~2008 Vanderbilt University，postdoctoral/Research Assistant Professor/Assistant Professor
2008~2016 Institute of Zoology，Chinese Academy of Sciences,fellow

2016- present: Professor, School of life sciences, Xiamen University

Selected Publications(* Corresponding author)：

1. Xin Q#, Kong S#, Yan J#, Qiu J, He B, Zhou C, Ni Z, Bao H, Huang L, Lu J, Xia G, Liu X*, Chen Z*, Wang C*, Wang H*. Bmi-1 determines uterine progesterone responsiveness essential for normal embryo implantation. J Clin Invest. 128(1):175-189, 2018
2. Cui T, He B, Kong S, Zhou C, Zhang H, Ni Z, Bao H, Qiu J, Xin Q, Reinberg D, Lydon JP, Lu J*, Wang H*. PR-Set7 deficiency limits uterine epithelial population growth hampering postnatal gland formation in mice. Cell Death Differ. Dec;24(12):2013-2021, 2017
3. Ran H#, Kong S#, Zhang S#, Cheng J, Zhou C, He B, Xin Q, Lydon JP, DeMayo FJ, Feng GS, Xia G, Lu Z*, Wang C*, Wang H*. Nuclear Shp2 directs normal embryo implantation via facilitating the ERα tyrosine phosphorylation by the Src kinase. Proc Natl Acad Sci U S A. 114(18):4816-4821, 2017
4. Tu Z, Wang Q, Cui T, Wang J, Ran H, Bao H, Lu J, Wang B, Lydon JP, DeMayo F, Zhang S, Kong S*, Wu X*, Wang H*. Uterine RAC1 via Pak1-ERM signaling directs normal luminal epithelial integrity conducive to on-time embryo implantation in mice. Cell Death Differ. 23(1):169-81, 2016
5. Zhang S#, Kong S#, Wang B, Cheng X, Chen Y, Wu W, Wang Q, Shi J, Zhang Y, Wang S, Lydon JP, DeMayo F, Pear WS, Han H, Lin H, Li L, Wang HM, Wang YL, Li B, Chen Q*, Duan E*, Wang H*. Uterine Rbpj is required for embryo-uterine orientation and decidual remodeling via Notch pathway- independent and -dependent mechanisms. Cell Res., 24(8):925-42, 2014
6.Lu J, Zhang S, Nakano H, Simmons DG, Wang S, Kong S, Wang Q, Shen L, Tu Z, Wang W, Wang B, Wang HM, Wang Y, van Es JH, Clevers H, Leone G, Cross JC*, Wang H*. A positive feedback loop involving gcm1 and fzd5 directs chorionic branching morphogenesis in the placenta. PLoS Biol. 11(4):e1001536, 2013
7. Lim H* & Wang H*. Uterine disorders and pregnancy complications: insights from mouse models. J CIin Invest. 120(4), 1004-15, 2010
8. Xie H, Tranguch S, Jia X, Zhang H, Das SK, Dey SK, Kuo CJ, and Wang H. Inactivation of Nuclear Wnt-β-Catenin Signaling Limits Blastocyst Competency for Implantation. Development. 135: 717-727, 2008
9. Xie H#, Wang H#, Tranguch S, Iwamoto R, Mekada E, DeMayo FJ, Lydon JP, Das SK and Dey SK. Maternal heparin-binding-EGF deficiency limits pregnancy success in mice.Proc Natl Acad Sci USA. 104(46): 18315-20, 2007
10. Wang H and Dey SK. Roadmap to embryo implantation: Clues from mouse models. Nature Review Genetics. 7 (3): 185-199, 2006
11. Wang H, Xie H, Guo Y, Zhang H, Takahashi T, Kingsley PJ, Marnett LJ, Das SK, Cravatt BF and Dey SK. Fatty acid amide hydrolase deficiency limits early pregnancy events. J CIin Invest. 116 (8): 2122-2131, 2006
12. Wang H#, Tranguch S#, Xie H, Hanley G, Das SK, Dey SK. Variation in commercial rodent diets induces disparate molecular and physiological changes in the mouse uterus. Proc Natl Acad Sci USA.102 (28): 9960-9965, 2005
13.Wang H, Guo Y, Wang D, Kingsley PJ, Marnett LJ, Das SK,DuBois RN and Dey SK. Aberrant cannabinoid signaling impairs oviductal transport of embryos. Nature Medicine.10: 1074-1080, 2004
14. Wang H, Matsumoto H, Guo Y, Paria BC, Roberts RL, and Dey SK. Differential G-Protein coupled cannabinoid receptor signaling by anandamide directs blastocyst activation for implantation. Proc Natl Acad Sci USA. 100(25): 14914-14919, 2003