Education

B.S. 2009, East China University of Science and Technology, Bioengineering;
M.S. 2012, East China University of Science and Technology, Microbiological and Biochemical Pharmacy;
Ph.D. 2018, Technical University of Munich, Bioinformatics;

Professional Experience

Lecture, School of Medicine, Huaqiao University, 2018-2023
Assistant Professor, School of Life Sciences, Xiamen University, 2023 to present

Research Area

My research focuses on the field of RNA, primarily involving the identification, structure determination, evolution, and functional studies of novel RNA structural elements, such as ribozymes. Additionally, I investigate the regulatory mechanisms of the translation process involving RNA, and conduct research in disease diagnosis and treatment based on transcriptomics. My work contributes to understanding the roles of RNA in cellular processes and its implications for potential therapeutic applications.

Selected Publications

1.Qi, F.^*, Chen, J., Chen, Y., Sun, J., Lin, Y., Chen, Z., Kapranov P.^* Evaluating Performance of Different RNA Secondary Structure Prediction Programs Using Self-cleaving Ribozymes. Genomics, Proteomics & Bioinformatics. 2024,22(3):qzae043.
2.Chen, Y.^#, Qi, F.^#*, Gao, F., Cao, H., Xu, D., Salehi-Ashtiani, K., Kapranov, P.^* Hovlinc is a recently evolved class of ribozyme found in human lncRNA. Nat Chem Biol. 2021,17(5):601–607.
3.Qi, F., Frishman, D. Melting temperature highlights functionally important RNA structure and sequence elements in yeast mRNA coding regions. Nucleic Acids Res. 2017,45(10):6109–6118.
4.Krafczyk, R.^#, Qi, F.^#, Sieber, A., Mehler, J., Jung, K., Frishman, D.^*, Lassak, J.^* Proline codon pair selection determines ribosome pausing strength and translation efficiency in bacteria. Commun Biol. 2021,4(1):589.
5.Qi, F., Motz, M., Jung, K., Lassak, J., Frishman, D. Evolutionary analysis of polyproline motifs in Escherichia coli reveals their regulatory role in translation. PLOS Comput Biol. 2018,14(2):e1005987.
6.Qi, F., Gao, F., Cai, Y., Han, X., Ni, J., Sun, J., Huang, S., Chen, S., Wu, C., Kapranov, P. Complex age- and cancer-related changes in human blood transcriptome – implications for pan-cancer diagnostics. Front Genet. 2021,12:746879.
7.Qi, F., Cai, Y., Chen, J., Han, X., Xia, Q., Kapranov, P. Traditional Chinese medicine treatment, Gua Sha, can induce subtle molecular changes in gene expression. Biomed Environ Sci. 2023, 36(5): 441-451.