Post on: 2016-05-30Source: Hits: 943

Tong CHENG, Ph.D.

Associate Professor.

Tel: +86-592-2184113



1999, B.Sc., Xiamen University;

2006, Ph.D., Xiamen University.

Selected Publications

1. Xu L, He D, Yang L, Li Z, Ye X, Yu H, Zhao H, Li S, Yuan L, Qian H, Que Y, Kuo Shih JW, Zhu H, Li Y, Cheng T*, Xia N*. A Broadly Cross-protective Vaccine Presenting the Neighboring Epitopes within the VP1 GH Loop and VP2 EF Loop of Enterovirus 71. Scientific Reports. 2015, 5:12973.

2. Yang L, Li S, Liu Y, Hou W, Lin Q, Zhao H, Xu L, He D, Ye X, Zhu H, Cheng T*, Xia N. Construction and characterization of an infectious clone of coxsackievirus A6 that showed high virulence in neonatal mice. Virus Res. 2015, 210:165-168.

3. Liu J, Zhu R, Ye X, Yang L, Wang Y, Huang Y, Wu J, Wang W, Ye J, Li Y, Zhao Q, Zhu H, Cheng T*, Xia N. A monoclonal antibody-based VZV Glycoprotein E Quantitative Assay and Its Application on Antigen Quantitation in VZV Vaccine. Appl Microbiol Biotechnol, 2015, 99(11):4845-4853

4. Hou W, Yang L, Li S, Yu H, Xu L, He D, Chen M, He S, Ye X, Que Y, Shih JW, Cheng T*, Xia N*. Construction and characterization of an infectious cDNA clone of Echovirus 25. Virus Res. 2015, 205:41-44

5. Hou W, Yang L, He D, Zheng J, Xu L, Liu J, Liu Y, Zhao H, Ye X, Cheng T*, Xia N. Development of a coxsackievirus A16 neutralization test based on the enzyme-linked immunospot assay. J Virol Methods. 2015, 215-216:56-60

6. Xu L, He D, Li Z, Zheng J, Yang L, Yu M, Yu H, Chen Y, Que Y, Shih JW, Liu G, Zhang J, Zhao Q, Cheng T*, Xia N. Protection against lethal Enterovirus 71 challenge in mice by a recombinant vaccine candidate containing a broadly cross-neutralizing epitope within the VP2 EF loop. Theranostics. 2014, 4(5):498-513. (cover paper)

7. Yang L, He D, Tang M, Li Z, Liu C, Xu L, Chen Y, Du H, Zhao Q, Zhang J, Cheng T*, Xia N. Development of an enzyme-linked immunosorbent spot assay to measure serum-neutralizing antibodies against coxsackievirus B3. Clin Vaccine Immunol. 2014, 21(3):312-20.

8. Li Z, Xu L, He D, Yang L, Liu C, Chen Y, Shih JW, Zhang J, Zhao Q, Cheng T*, Xia N*. In Vivo Time-Related Evaluation of a Therapeutic Neutralization Monoclonal Antibody against Lethal Enterovirus 71 Infection in a Mouse Model. PLoS One. 2014, 9(10):e109391.

9. Chen L, Liu J, Wang W, Ye J, Wen L, Zhao Q, Zhu H, Cheng T*, Xia N. Development of a Varicella-zoster virus neutralization assay using a glycoprotein K antibody enzyme-linked immunosorbent spot assay. J Virol Methods, 2014, 200C:10-14. 

10. Mao Q1, Cheng T1, Zhu F1, Li J, Wang Y, Li Y, Gao F, Yang L, Yao X, Shao J, Xia N, Liang Z, Wang J. The cross-neutralizing activity of enterovirus 71 subgenotype c4 vaccines in healthy chinese infants and children. PLoS One. 2013, 8(11):e79599. co-1st

11. Wang W, Cheng T*, Ma K, Xia D, Wang Y, Liu J, Du H, Shih JW, Zhang J, Zhao Q, Xia N. Development of a novel baculovirus titration method using the Enzyme-linked immunosorbent spot (ELISPOT) assay. J Virol Methods. 2013, 188(1-2):114-20.

12. Zhang T1, Cheng T1, Wei L, Cai Y, Yeo AE, Han J, Yuan YA, Zhang J, Xia N. Efficient inhibition of HIV-1 replication by an artificial polycistronic miRNA construct. Virol J. 2012, 9(1):118. co-1st

13. Zhang YL, Cheng T*, Cai YJ, Yuan Q, Liu C, Zhang T, Xia DZ, Li RY, Yang LW, Wang YB, Yeo AE, Shih JW, Zhang J, Xia NS. RNA Interference inhibits hepatitis B virus of different genotypes in vitro and in vivo. BMC Microbiol. 2010, 10:214.

14. Spiess K, Jeppesen MG, Malmgaard-Clausen M, Krzywkowski K, Dulal K, Cheng T, Hjortø GM, Larsen O, Burg JS, Jarvis MA, Garcia KC, Zhu H, Kledal TN, Rosenkilde MM. Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus infection in vivo. Proc Natl Acad Sci USA. 2015. pii: 201509392

15. Selariu A, Cheng T, Tang Q, Silver B, Yang L, Liu C, Ye X, Markus A, Goldstein RS, Cruz Cosme RS, Lin Y, Wen L, Qian H, Han J, Dulal K, Huang Y, Li Y, Xia N, Zhu H. ORF7 of Varicella Zoster Virus is a Neurotropic Factor.J Virol. 2012 , 86(16):8614-24.

16. Chen Y, Li C, He D, Cheng T, Ge S, Shih JW, Zhao Q, Chen PJ, Zhang J, Xia N. Antigenic analysis of divergent genotypes human Enterovirus 71 viruses by a panel of neutralizing monoclonal antibodies: Current genotyping of EV71 does not reflect their antigenicity. Vaccine. 2013, 31(2):425-30.

17. Zhang Z, Selariu A, Warden C, Huang G, Huang Y, Zaccheus O, Cheng T, Xia N, Zhu H. Genome-wide mutagenesis reveals that ORF7 is a novel VZV skin-tropic factor. PLoS Pathog. 2010, 6(7):e1000971.