Runzhong LIU

Post on: 2016-05-30Source: Hits: 647

Runzhong LIU, Ph.D.

Associate Professor.

Tel: +86-592-2181312



1982, B.Sc., Jiangxi University;

1990, M.Sc., Wuhan Institute of Virology, The Chinese Academy of Sciences;

2006, Ph.D., Biochemistry and Molecular Biology, School of Life Sicences, Xiamen University.

Professional Experience

1991, Assistant researcher in Wuhan Institute of Virology, The Chinese Academy Sciences;

1996, Associate researcher in Wuhan Institute of Virology, The Chinese Academy Sciences;

1997-2000, Cornell University as a visiting scholar;

2000-2001, University of Arkanses Medical Sciences as a visiting scholar;

2002, Associate professor in School of Life Sicences, Xiamen University;

2004-2005, The Burnham Institute (San Diego).

Research Area

Our research focuses on understanding the molecular events that underlie the pathogenesis of neurodegenative diseases such as Alzheimer’s disease (AD) and the mechanism of positive transcriptional elongation factor b(P-TEFb) regulation transcription in neural stem cells. Especially on the mechanism of the HIV-1 Tat protein regulation P-TEFb of neurons for neurodegenative diseases.

Selected Publications

1. Hu X, Lu X, Liu R, Ai N, Cao Z, Li Y, Liu J, Yu B, Liu K, Wang H, Zhou C, Wang Y, Han A, Ding F, Chen R. Histone cross-talk connects protein phosphatase 1α (PP1α) and histone deacetylase (HDAC) pathways to regulate the functional transition of bromodomain-containing 4 (BRD4) for inducible gene expression. J Biol Chem. 2014;289(33):23154-67.

2. Lin D, Wang Q, Ran H, Liu K, Wang Y, Wang J, Liu Y, Chen R, Sun Y, Liu R, Ding F.Abnormal response to the anorexic effect of GHS-R inhibitors andexenatide in male Snord116 deletion mouse model for Prader-Willi syndrome.Endocrinology. 2014 ;155(7):2355-62.

3. Huiping Wang, Xinxing Zhu, Ying Zhu, Jiangfang Liu, Xiangming Hu, Yu Wang, Sijia Peng, Yanheng Chen, Ruichuan Chen, Feng Ding, and Runzhong Liu. Protein Kinase D3 Is Essential for Prostratin-Activated Transcription of Integrated HIV-1 Provirus Promoter via NF-KB Signaling Pathway. Biomed Res Int. Volume 2014 ; 1-11 .

4. Runzhong Liu, Haibo Hou, Xuelian Yi, Shanwen Wu, Huan Zeng. Divalent cation tolerance protein binds to β-secretase and inhibits the processing of amyloid precursor protein. Neural Regeneration Research 2013; 8(11):991-999.