Zhe CHENG, Ph.D.
1999-2003, B.Sc., School of Life Science, Northwest University (Xi'an);
2003-2009, Ph.D., School of Life Sciences, Xiamen University;
2006-2007, Utah State University，exchange scholar.
We utilize E. multilocularis, one of the most important human helminthic pathogens, as the experimental model to investigate the impacts of host factors on the parasite’s growth and development, including the role of host factor-mediated signaling pathways in the parasite’s growth and development, and the contributions of host derived factors to E. multilocularis germinative cell self-renewal and pluripotency maintenance.
1. Identification and characterisation of Emp53, the homologue of human tumor suppressor p53, from Echinococcus multilocularis: its role in apoptosis and the oxidative stress response. Int J Parasitol. 2015, 45(8):517-526.
2. A rapid and convenient method for fluorescence analysis of in vitro cultivated metacestode vesicles from Echinococcus multilocularis. PLoS One, 2015, 10: e0118215.
3. The effect of tributyltin chloride on Caenorhabditis elegans germline is mediated by a conserved DNA damage check-point pathway. Toxicol Lett. 2014, 21, 225(3): 413-421.
4. Morphological and structural characterization of haemocytes of Oncomelania hupensis (Gastropoda: Pomatiopsidae). Italian Journal of Zoology, 2013, 1–9.
5. Echinococcus multilocularis: Proteomic analysis of the protoscoleces by two-dimensional electrophoresis and mass spectrometry. Exp Parasitol. 2009, 123(2):162-167.