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瞿清明教授

邮  箱:quqingming@xmu.edu.cn

职称/职务:教授 博士生导师

联系方式:

  • 个人简介
  • 科研领域
  • 代表性成果

2007年,北京大学地球化学专业,学士学位;
2010年,中国科学院古脊椎动物古人类研究所古生物学与地层学,硕士学位;
2015年,瑞典乌普萨拉大学进化生物学中心,博士学位;
2015-2019年,瑞典乌普萨拉大学进化生物学中心/加拿大渥太华大学生物系,博士后;
2019年,厦门大学生命科学学院,教授、博士生导师。
B.S. 2007, Peking University, Geochemistry;
M.S. 2010, Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Paleontology and Stratigraphy;
Ph.D. 2015, Evolutionary Biology Center, Uppsala University, Sweden;
Postdoc, Evolutionary Biology Center, Uppsala University, Sweden & Department of Biology, University of Ottawa, Canada, 2015-2019;
Professor, School of Life Sciences, Xiamen University, 2019 to Present.

本实验室主要从事比较基因组学和进化发育生物学研究,并以斑马鱼为实验动物模型,致力于回答以下科学问题:
1. 生物形态学性状的平行演化/趋同演化是否受到同源的基因组位点控制?
2. 表型和基因型的对应关系是如何在演化中发生改变的?
3. 发育限制(developmental constraints)在多大程度上决定了表型和基因型的演化方向?
4. 脊椎动物的附肢起源的遗传学机制是什么?
Our laboratory primarily focuses on comparative genomics and evolutionary developmental biology (evo-devo), using zebrafish as an experimental animal model. We aim to address the following scientific questions:
1. To what extent is the parallel evolution or convergent evolution of morphological traits controlled by homologous genomic loci?
2. How does the correspondence between phenotype and genotype change during evolution?
3. To what degree do developmental constraints influence the evolutionary direction of phenotypes and genotypes?
4. What are the genetic mechanisms underlying the origin of appendages in vertebrates?
欢迎对生物信息学和发育生物学感兴趣的学生来咨询,有计算机和数学背景的学生但不懂生物学的也欢迎邮件咨询,常年提供博后职位。

代表性论文(# co-first author, * Corresponding author):

1. Shi, C. et al. Q. Qu* and G. Li* (2024) Evolution of the gene regulatory network of body axis by enhancer hijacking in amphioxus. eLife 13, e89615.
2. Dong, Z., Wang, C. and Q. Qu*. (2024) WGCCRR: a web-based tool for genome-wide screening of convergent indels and substitutions of amino-acids. Bioinformatics Advances. https://doi.org:10.1093/bioadv/vbae070
3. Bremer, O., Q. Qu et al. (2022) Exploring the three-dimensional vasculature of dermal hard tissues in thyestiid osteostracans using synchrotron radiation microtomography. Journal of Vertebrate Paleontology 42, e2196318.
4. Bremer, O., Q. Qu et al. (2021) The emergence of a complex pore-canal system in the dermal skeleton of Tremataspis (Osteostraci). Journal of Morphology 282, 1141-1157. https://doi.org:https://doi.org/10.1002/jmor.21359
5. Cui, X., Q. Qu et al. (2021) Modeling scale morphogenesis in a Devonian chondrichthyan and scale growth patterns in crown gnathostomes. Journal of Vertebrate Paleontology, e1930018 (2021). https://doi.org:10.1080/02724634.2021.1930018
6. Qu, Q.*, S. Sanchez, M. Zhu, H. Blom and P. E. Ahlberg (2017). The origin of novel features by changes in developmental mechanisms: ontogeny and three‐dimensional microanatomy of polyodontode scales of two early osteichthyans. Biological Reviews. 92: 1189–1212
7. Choo, C., M. Zhu, Q. Qu, X Yu, L. Jia and W. Zhao (2017). A new osteichthyan from the late Silurian of Yunnan, China. PloS one. 12: e0170929
8. Jerve, A., Q. Qu, S. Sanchez, H. Blom, P. E. Ahlberg and T. Haitina (2017). Vascularization and odontode structure of a dorsal ridge spine of Romundina stellina Ørvig 1975. PloS one 12: e0189833
9. Jerve, A., Q. Qu, S. Sanchez, H. Blom and P. E. Ahlberg. (2016) Three-dimensional paleohistology of the scale and median fin spine of Lophosteus superbus (Pander 1856) PeerJ4:e2521 (Co-first author)
10. Qu, Q.*, H. Blom, S. Sanchez and P. Ahlberg (2015). Three‐dimensional virtual histology of Silurian osteostracan scales revealed by synchrotron radiation.Journal of Morphology, 276: 873-888.
11. Qu, Q. ,T. Haitina, M. Zhu and P. E. Ahlberg* (2015). New genomic and fossil data illuminate the origin of enamel. Nature 526, 108–111.
12. Qu, Q. *, S. Sanchez, H. Blom, P. Tafforeau and P. E. Ahlberg (2013). Scales and tooth whorls of ancient fishes challenge distinction between external and oral ‘teeth’. PloS one 8: e71890.
13. Qu, Q. *, M. Zhu and W. Wang (2013). Scales and dermal skeletal histology of an early bony fish Psarolepis romeri and their bearing on the evolution of rhombic scales and hard tissues. PloS one 8: e61485.
14. Qu, Q. *, M. Zhu and W.-J. Zhao (2010). Silurian atmospheric O2 changes and the early radiation of gnathostomes. Palaeoworld19: 146-159.
15. Wang, W., Q. Qu and M. Zhu* (2010). A brief review of the Middle Palaeozoic vertebrates from Southeast Asia. Palaeoworld 19: 27-36.
16. Zhu, M.*, X. Yu, P. E. Ahlberg, B. Choo, J. Lu, T. Qiao, Q. Qu, W. Zhao, L. Jia and H. Blom (2013). A Silurian placoderm with osteichthyan-like marginal jaw bones. Nature 502: 188-193.
17. Zhu, M.*, X. Yu, B. Choo, Q. Qu, L. Jia, W. Zhao, T. Qiao and J. Lu (2012). Fossil fishes from China provide first evidence of dermal pelvic girdles in osteichthyans. PloS one 7: e35103.
18. Zhu, M.*, W. Zhao, L. Jia, J. Lu, T. Qiao and Q. Qu (2009). The oldest articulated osteichthyan reveals mosaic gnathostome characters. Nature 458: 469-474.

荣誉、奖励及参加学术团体的情况: