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| 韩家淮教授博导 | ||||
| 顶 热 荐 作者:佚名 师资队伍来源:本站原创 点击数: 更新时间:2005-7-5 | ||||
主要研究领域(Research Area) Humans are under near constant attacks from bacteria, fungi, viruses and parasites. A person’s health is also affected by pathological changes during the course of his/her life. To maintain a healthy condition, the immune system has to not only protect the body from foreign pathogens but also recognize and eliminate the sick cells or tissues of its own. Immuno-responses can be classified as innate and adaptive immunities. Our research focuses on defining the intracellular signaling pathways in the innate immune system. Our research has revealed the p38 signal transduction pathway and demonstrated an important role of this pathway in promoting inflammation and in preventing tumorigenesis. We apply approaches of biochemistry, cell biology, forward and reverse genetics to address the mechanisms of innate immuno-responses. We are currenty useing Drosophila melanogaster, mouse, and cultured mammalian cells as model systems to study questions in immunity. We believe our research will bring out new information and ideas for therapeutic intervention of many human diseases.
主要学术成就 韩家淮教授在世界上率先发现p38信号通路。细胞内存在多条信号通路以介导不同的生物学反应。p38信号通路是细胞内最重要的信号通路之一,它在许多生物学反应包括细胞周期调控、细胞增殖、发育、分化、衰老、凋亡、免疫反应及肿瘤发生中起重要作用。估计世界上约有两千余家实验室涉足p38信号通路的研究,韩家淮教授领导的实验室在该领域一直保持世界领先地位。 韩家淮教授简历(Jiahuai Han:CURRICULUM VITAE) 我们的实验室 http://life.xmu.edu.cn/hanlab/
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