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黄秋英助理教授

发布时间:2015-12-19来源:点击数:4968

黄秋英 HUANG Qiuying, Ph.D.                              

助理教授

电  话:+86-592-2187992

E-mail: hqying@xmu.edu.cn

 

2000-2004, 厦门大学生命科学学院, 获理学学士学位

2004-2009,厦门大学生命科学学院,获理学博士学位

2009-2010,美国犹他大学病理系,任研究助理

2011年至今,厦门大学生命科学学院,任助理教授

 

C.V. 2000-2004, B.SC. School of Life Science, Xiamen University, China; 2004-2009, Ph.D. School of Life Science, Xiamen University, China; 2009-2010, Research Associate, Department of Pathology, The University of Utah, USA; 2011-present, Assistant Professor, School of Life Science, Xiamen University, China.

 

研究领域(Research Area)

以重大危害遗传病诊断和肿瘤基因突变检测为模型,从事分子诊断新技术和新方法的开发。

My research focuses on developing new techniques and methods for molecular diagnosis, with goals to provide better ways to diagnose human genetic disorders and detect somatic gene mutations in cancer.  

 

代表性论文 (Selected Publications)

1.Huang Q, Wang X, Tang N, Yan T, Chen P*, Li Q*.Simultaneous Genotyping of α-Thalassemia Deletional and Nondeletional Mutations by Real-Time PCR-Based Multicolor Melting Curve Analysis.J Mol Diagn. 2017Jul;19(4):567-574.

2.Wang X, Hong Y, Cai P, Tang N, Chen Y, Yan T, Liu Y, Huang Q*, Li Q*.Rapid and Reliable Detection of Nonsyndromic Hearing Loss Mutations by Multicolor Melting Curve Analysis.Sci Rep. 2017 Feb 22;7:42894.(*Co-corresponding author)

3.Xia Z#, Chen P, Tang N, Yan T, Zhou Y, Xiao Q, Huang Q*, Li Q*.Rapid detection of G6PD mutations by multicolor melting curve analysis.Mol Genet Metab. 2016 Sep;119(1-2):168-73.(*Co-corresponding author)

4.Huang Q, Wang X, Tang N, Zhu C, Yan T, Chen P*, Li Q*.Rapid detection of non-deletional mutations causing α-thalassemia by multicolor melting curve analysis.Clin Chem Lab Med. 2016 Mar;54(3):397-402.

5.Liao Y, Wang X, Sha C, Xia Z, Huang Q*, Li Q*. Combination of fluorescence color and melting temperature as a two-dimensional label for homogeneous multiplex PCR detection. Nucleic Acid Research, 2013 Apr 1;41(7):e76. (*Co-corresponding author)

6.Dempsey-Nunez L, Illson ML, Kent J, Huang Q, Brebner A, Watkins D, Gilfix BM, Wittwer CT, Rosenblatt DS . High resolution melting analysis of the MMAA gene in patients with cblA and in those with undiagnosed methylmalonicaciduria. Mol Genet Metab. 2012, 107(3):363-367.

7.Xiong F#, Huang Q#, Chen X, Zhou Y, Zhang X, Cai R, Chen Y, Xie J, Feng S, Wei X, Xiao Q, Zhang T, Luo S, Yang X, Hao Y, Qu Y, Li Q , Xu X. A Melting Curve Analysis–Based PCR Assay for One-Step Genotyping of β-Thalassemia Mutations: A Multicenter Validation. The Journal of Molecular Diagnostics. 2011,13(4): 427-435.(#Co-first author)

8.Huang Q, Liu Z, Liao Y, Chen X, Zhang Y, Li Q . Multicolor Fluorescence Melting Curve Analysis for Detection of Multiple Mutations with Self-Quenched Probes. PLoS ONE, 2011, 6(4):e19206.

9.Huang Q, Zheng L, Zhu Y, Zhang J, Wen H, Huang J, Niu J, Zhao X, Li Q . Multicolor combinatorial probe coding for real-time PCR. PLos ONE, 2011,6(1):e16033.

10.Huang Q, Li Q. Characterization of the 5′ to 3′ nuclease activity of Thermusaquaticus DNA polymerase on fluorogenic double-stranded probes. Mol Cell Probes. 2009 Jun-Aug; 23(3-4): 188-194.

11.Huang Q, Hu Q, Li Q. Identification of 8 Foodborne Pathogens by Multicolor Combinational Probe Coding Technology in a Single Real-Time PCR. Clinical Chemistry, 2007, 53(10): 1741-1748.

12.Huang Q, Cheng Y, Guo Q, Li Q. Preparation of a Chimeric Armored RNA as a Versatile Calibrator for Multiple Virus Assays. Clinical Chemistry, 2006, 52(7): 1446-1448.