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石艳副教授

发布时间:2015-04-20来源:点击数:4403

 

 

石艳 SHI Yan Ph.D.石艳副教授教授

副教授硕士生导师

电话:+86-592-2184648

E-mail:yshi@xmu.edu.cn

 

1991.9-1995.7,厦门大学生物化学专业,学士学位;

1995.8-1998.7,中科大研究生院生物化学与分子生物学专业,硕士学位;

1998.8-2000.11,厦门大学生物系助教;

2002.9-2006.12,厦门大学生物化学与分子生物学专业,博士学位;

2000.12-2007.7,厦门大学生命科学学院讲师;

2007.8-至今任厦门大学生命科学学院副教授;

2009.8-2010.9美国范德堡大学医学中心访问学者。

 

研究领域(Research Area

 酶的分离纯化、结构与功能,构象与活力的关系,酶活力调控机理,抑制作用机理,酶产品的开发与应用,蛋白质组学研究。

My research is focused on Enzymology, including structure and function of enzyme, kinetics of enzyme, regulation mechanism of enzymatic activity; Enzyme inhibitor research; Proteomics research.

 

代表性论文(Selected Publications

1.  Chai WM, Shi Y; Feng HL, Qiu L, Zhou HC, Deng ZW, Yan CL, Chen QX. NMR, HPLC-ESI-MS, and MALDI-TOF MS Analysis of Condensed Tannins from Delonix regia (Bojer ex Hook.) Raf. and Their Bioactivities, J Agric Food Chem., 2012, 60 (19): 5013-5022. (co-first author)

2.    Wang LH, Liu LP, Shi Y, Cao HW, Chaturvedi R, Calcutt MW, Hu TH, Ren XB, Wilson KT, Polk DB, Yan F. Berberine Induces Caspase-Independent Cell Death in Colon Tumor Cells through Activation of Apoptosis-Inducing Factor, PLOS ONE, 7(5): e36418.

3.    Yan F, Cao HW, Cover TL, Washington MK, Shi Y, Liu LS, Chaturvedi R, Peek Jr RM, Wilson KT, Polk DB. Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism, J Clin Invest. 2011; 121(6):2242–2253.

4.    Shi Y, Tao YM, Ma SJ, An G, Long MN, Chen QX. Purification and some properties of endoglucanase from Glyptotermes xiamenensis, Journal of Applied Entomology, 2010, 134(9-10):789–797.

5.    Liao JH, Chen QX, Zhang Q, Yang Y, Shi Y*. Unfolding and Inactivation of Abalone (Haliotis diversicolor) Alkaline Phosphatase during denaturation by guanidine hydrochloride. Appl Biochem Biotechnol. 2009, 158: 323–333.

6.    Shi Y, Jiang Z, Han P, Zheng GX, Song,K K, Chen Q X. Purification and some properties of β-N-Acetyl-D-glucosaminidase from the cabbage butterfly (Pieris brassicae). Biochimie. 2007, 89(3):347-54.

7.    Xie XL, Shi Y, Huang QS, Chen QX. Inactivation Kinetics of β-N-Acetyl-D- Glucosaminidase from Prawn (Penaeus vannamei) by Formaldehyde. Marine Science Bulletin. 2006, 8(1): 34~45.

8.    Song KK, Huang H, Han P, Zhang CL, Shi Y, Chen QX. Inhibitory effects of cis- and trans- isomers of 3,5-dihydroxystilbene on the activity of mushroom tyrosinase. Biochem. Biophys. Res. Commun. 2006, 342: 1147-1151.

9.    Shi Y, Chen QX, Wang Q, Song KK, Qiu L. Inhibitory effects of cinnamic acid and its drrivatives on the diphenolase activity of mushroom (Agaricus bisporus) tyrosinase,Food Chemistry, 2005, 92: 707-712.

10. Wang Q, Shi Y, Song KK, Guo HY, Qiu L, Chen QX. Inhibitory effects of 4-Halobenzoic acids on the diphenolase and monophenolase activity of mushroom tyrosinase. The Protein Journal, 2004, 23(5): 303-308.